7-methoxy-4-oxo-1,4-dihydro quinoline-2-carboxylic acid methyl ester
methyl 4-hydroxy-7-methoxyquinoline-2-carboxylate
CAS: 259214-73-8;77474-23-8
Molecular Formula: C12H11NO4
7-methoxy-4-oxo-1,4-dihydro quinoline-2-carboxylic acid methyl ester - Names and Identifiers
| Name | methyl 4-hydroxy-7-methoxyquinoline-2-carboxylate |
| Synonyms | methyl 4-hydroxy-7-methoxyquinoline-2-carboxylate 7-methoxy-4-oxo-1H-quinoline-2-carboxylic acid methyl ester 4-Hydroxy-7-methoxy-quinoline-2-carboxylic acid methyl ester 2-Quinolinecarboxylic acid, 4-hydroxy-7-methoxy-, methyl ester 7-methoxy-4-oxo-1,4-dihydro quinoline-2-carboxylic acid methyl ester |
| CAS | 259214-73-8 77474-23-8 |
| InChI | InChI=1/C12H11NO4/c1-16-7-3-4-8-9(5-7)13-10(6-11(8)14)12(15)17-2/h3-6H,1-2H3,(H,13,14) |
7-methoxy-4-oxo-1,4-dihydro quinoline-2-carboxylic acid methyl ester - Physico-chemical Properties
| Molecular Formula | C12H11NO4 |
| Molar Mass | 233.22 |
| Density | 1.317g/cm3 |
| Boling Point | 444.994°C at 760 mmHg |
| Flash Point | 222.925°C |
| Vapor Presure | 0mmHg at 25°C |
| Refractive Index | 1.624 |
7-methoxy-4-oxo-1,4-dihydro quinoline-2-carboxylic acid methyl ester - Introduction
methyl is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White to slightly yellow crystalline powder.
-Molecular formula: C12H11NO4.
-Molecular weight: 237.23g/mol.
-Melting point: 129-131 ° C.
-Solubility: Soluble in common organic solvents such as ethanol and chloroform.
Use:
methyl has many applications in chemical research and the pharmaceutical industry:
-As a drug intermediate: It can be used to synthesize a variety of drugs, such as antimalarial drugs and antibacterial drugs.
-Antibacterial activity: This compound has antibacterial effect and can inhibit the growth of pathogenic bacteria.
Method:
The preparation of methyl L can use common methods in synthetic organic chemistry. The following is a possible preparation method:
1. React 4-hydroxy-7-methoxyquinoline with formic acid.
2. The reaction is usually carried out in an organic solvent, commonly used with ethanol or chloroform.
3. When the reaction proceeds, heating and stirring are usually required to promote the progress of the reaction.
4. After the reaction, the product can be purified and isolated by crystallization or column chromatography.
Safety Information:
The safety of methyl L depends on its use and handling:
-When using in the laboratory, Please strictly follow the safety procedures and wear appropriate protective equipment.
-Avoid inhalation, contact with skin and eyes.
-When storing, keep it in a dry, cool place, away from fire and oxidizing agents.
-If necessary, consult your chemical supplier or poison control center for more detailed safety information.
Nature:
-Appearance: White to slightly yellow crystalline powder.
-Molecular formula: C12H11NO4.
-Molecular weight: 237.23g/mol.
-Melting point: 129-131 ° C.
-Solubility: Soluble in common organic solvents such as ethanol and chloroform.
Use:
methyl has many applications in chemical research and the pharmaceutical industry:
-As a drug intermediate: It can be used to synthesize a variety of drugs, such as antimalarial drugs and antibacterial drugs.
-Antibacterial activity: This compound has antibacterial effect and can inhibit the growth of pathogenic bacteria.
Method:
The preparation of methyl L can use common methods in synthetic organic chemistry. The following is a possible preparation method:
1. React 4-hydroxy-7-methoxyquinoline with formic acid.
2. The reaction is usually carried out in an organic solvent, commonly used with ethanol or chloroform.
3. When the reaction proceeds, heating and stirring are usually required to promote the progress of the reaction.
4. After the reaction, the product can be purified and isolated by crystallization or column chromatography.
Safety Information:
The safety of methyl L depends on its use and handling:
-When using in the laboratory, Please strictly follow the safety procedures and wear appropriate protective equipment.
-Avoid inhalation, contact with skin and eyes.
-When storing, keep it in a dry, cool place, away from fire and oxidizing agents.
-If necessary, consult your chemical supplier or poison control center for more detailed safety information.
Last Update：2024-04-09 02:00:44
